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1

Arterial Spin-Labeling Perfusion MRI Stratifies Progression-Free Survival and Correlates with Epidermal Growth Factor Receptor Status in Glioblastoma

Qiao, X. J., Ellingson, B. M., Kim, H. J., Wang, D. J. J., Salamon, N., Linetsky, M., Sepahdari, A. R., Jiang, B., Tian, J. J., Esswein, S. R., Cloughesy, T. F., Lai, A., Nghiemphu, L., Pope, W. B.

Journal:

American Journal of Neuroradiology

Year:

2015

Language:

english

File:

PDF, 1.32 MB

english, 2015

2

D-2-Hydroxyglutarate is Necessary and Sufficient for Isocitrate Dehydrogenase 1 Mutant-induced MIR148A Promoter Methylation

Li, Tie, Cox, Christopher D, Ozer, Byram, Nguyen, Nhung T, Nguyen, Huytram N, Lai, Thomas J, Li, Sichen, Liu, Fei, Kornblum, Harley I, Liau, Linda M, Nghiemphu, Phioanh Leia, Cloughesy, Timothy F., La

Journal:

Molecular Cancer Research

Year:

2018

Language:

english

File:

PDF, 3.24 MB

english, 2018

3

Simultaneous pH-sensitive and oxygen-sensitive MRI of human gliomas at 3 T using multi-echo amine proton chemical exchange saturation transfer spin-and-gradient echo echo-planar imaging (CEST-SAGE-EPI)

Harris, Robert J., Yao, Jingwen, Chakhoyan, Ararat, Raymond, Catalina, Leu, Kevin, Liau, Linda M., Nghiemphu, Phioanh L., Lai, Albert, Salamon, Noriko, Pope, Whitney B., Cloughesy, Timothy F., Ellings

Journal:

Magnetic Resonance in Medicine

Year:

2018

Language:

english

File:

PDF, 903 KB

english, 2018

4

Rate of change in maximum 18F-FDOPA PET uptake and non-enhancing tumor volume predict malignant transformation and overall survival in low-grade gliomas

Oughourlian, Talia C., Yao, Jingwen, Schlossman, Jacob, Raymond, Catalina, Ji, Matthew, Tatekawa, Hiroyuki, Salamon, Noriko, Pope, Whitney B., Czernin, Johannes, Nghiemphu, Phioanh L., Lai, Albert, Cl

Journal:

Journal of Neuro-Oncology

Year:

2020

Language:

english

File:

PDF, 1.94 MB

english, 2020

5

QOLP-12. EVALUATION OF THE UCLA NEURO-ONCOLOGY PROGRAM PSYCHOSOCIAL PATIENT SCREENING FORM IN IDENTIFYING DEPRESSION, FATIGUE, AND PERCEIVED COGNITIVE FUNCTION IN PATIENTS WITH GLIOMAS

Choi, Justin, Van Dyk, Kathleen, Heimberg, Brandon F, Cloughesy, Timothy, Lai, Albert, Fong, Nanette, Michelson, Lauren, Vargas, Erika, Leia Nghiemphu, P

Journal:

Year:

2019

File:

PDF, 82 KB

2019

6

Nonlinear registration of diffusion-weighted images improves clinical sensitivity of functional diffusion maps in recurrent glioblastoma treated with bevacizumab

Benjamin M. Ellingson, Timothy F. Cloughesy, Albert Lai, Phioanh L. Nghiemphu, Whitney B. Pope

Journal:

Magnetic Resonance in Medicine

Year:

2012

Language:

english

File:

PDF, 1.94 MB

english, 2012

7

Phase II Pilot Study of Bevacizumab in Combination with Temozolomide and Regional Radiation Therapy for Up-Front Treatment of Patients With Newly Diagnosed Glioblastoma Multiforme: Interim Analysis of Safety and Tolerability

Albert Lai, Emese Filka, Bruce McGibbon, Phioanh Leia Nghiemphu, Carrie Graham, William H. Yong, Paul Mischel, Linda M. Liau, Marvin Bergsneider, Whitney Pope, Michael Selch, Tim Cloughesy

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

2008

Language:

english

File:

PDF, 254 KB

english, 2008

8

Time course of imaging changes of GBM during extended bevacizumab treatment

Suchitra Ananthnarayan, Jennie Bahng, James Roring, Phioanh Nghiemphu, Albert Lai, Timothy Cloughesy, Whitney B. Pope

Journal:

Journal of Neuro-Oncology

Year:

2008

Language:

english

File:

PDF, 457 KB

english, 2008

9

Cell invasion, motility, and proliferation level estimate (CIMPLE) maps derived from serial diffusion MR images in recurrent glioblastoma treated with bevacizumab

Benjamin M. Ellingson, Timothy F. Cloughesy, Albert Lai, Phioanh L. Nghiemphu, Whitney B. Pope

Journal:

Journal of Neuro-Oncology

Year:

2011

Language:

english

File:

PDF, 2.01 MB

english, 2011

10

Quantification of edema reduction using differential quantitative T2 (DQT2) relaxometry mapping in recurrent glioblastoma treated with bevacizumab

Benjamin M. Ellingson, Timothy F. Cloughesy, Albert Lai, Phioanh L. Nghiemphu, Shadi Lalezari, Taryar Zaw, Kourosh Motevalibashinaeini, Paul S. Mischel, Whitney B. Pope

Journal:

Journal of Neuro-Oncology

Year:

2012

Language:

english

File:

PDF, 467 KB

english, 2012

11

Comparison between intensity normalization techniques for dynamic susceptibility contrast (DSC)-MRI estimates of cerebral blood volume (CBV) in human gliomas

Benjamin M. Ellingson, Taryar Zaw, Timothy F. Cloughesy, Kourosh M. Naeini, Shadi Lalezari, Sandy Mong, Albert Lai, Phioanh L. Nghiemphu, Whitney B. Pope

Journal:

Journal of Magnetic Resonance Imaging

Year:

2012

Language:

english

File:

PDF, 1.04 MB

english, 2012

12

Apparent diffusion coefficient histogram analysis stratifies progression-free and overall survival in patients with recurrent GBM treated with bevacizumab: a multi-center study

Whitney B. Pope, Xin Joe Qiao, Hyun J. Kim, Albert Lai, Phioanh Nghiemphu, Xi Xue, Benjamin M. Ellingson, David Schiff, Dawit Aregawi, Soonmee Cha, Vinay K. Puduvalli, Jing Wu, Wai-Kwan A. Yung, Geoff

Journal:

Journal of Neuro-Oncology

Year:

2012

Language:

english

File:

PDF, 364 KB

english, 2012

13

Proteasomal and Genetic Inactivation of the NF1 Tumor Suppressor in Gliomagenesis

Lauren T. McGillicuddy, Jody A. Fromm, Pablo E. Hollstein, Sara Kubek, Rameen Beroukhim, Thomas De Raedt, Bryan W. Johnson, Sybil M.G. Williams, Phioanh Nghiemphu, Linda M. Liau, Tim F. Cloughesy, Pau

Journal:

Year:

2009

Language:

english

File:

PDF, 896 KB

english, 2009

14

Regional and Voxel-Wise Comparisons of Blood Flow Measurements Between Dynamic Susceptibility Contrast Magnetic Resonance Imaging (DSC-MRI) and Arterial Spin Labeling (ASL) in Brain Tumors

Carissa M. White, Whitney B. Pope, Taryar Zaw, Joe Qiao, Kourosh M. Naeini, Albert Lai, Phioanh L. Nghiemphu, J.J. Wang, Timothy F. Cloughesy, Benjamin M. Ellingson

Journal:

Journal of Neuroimaging

Year:

2012

Language:

english

File:

PDF, 907 KB

english, 2012

15

Differential Sensitivity of Glioma- versus Lung Cancer-Specific EGFR Mutations to EGFR Kinase Inhibitors

Vivanco, I., Robins, H. I., Rohle, D., Campos, C., Grommes, C., Nghiemphu, P. L., Kubek, S., Oldrini, B., Chheda, M. G., Yannuzzi, N., Tao, H., Zhu, S., Iwanami, A., Kuga, D., Dang, J., Pedraza, A., B

Journal:

Cancer Discovery

Year:

2012

Language:

english

File:

PDF, 4.26 MB

english, 2012

16

A Phase I Trial of Tipifarnib With Radiation Therapy, With and Without Temozolomide, for Patients With Newly Diagnosed Glioblastoma

Phioanh Leia Nghiemphu, Patrick Y. Wen, Kathleen R. Lamborn, Jan Drappatz, H. Ian Robins, Karen Fink, Mark G. Malkin, Frank S. Lieberman, Lisa M. DeAngelis, Alejandro Torres-Trejo, Susan M. Chang, Lau

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

2011

Language:

english

File:

PDF, 178 KB

english, 2011

17

A dose escalation trial for the combination of erlotinib and sirolimus for recurrent malignant gliomas

Phioanh Leia Nghiemphu, Albert Lai, Richard M. Green, David A. Reardon, Timothy Cloughesy

Journal:

Journal of Neuro-Oncology

Year:

2012

Language:

english

File:

PDF, 194 KB

english, 2012

18

Anatomic localization of O6-methylguanine DNA methyltransferase (MGMT) promoter methylated and unmethylated tumors: A radiographic study in 358 de novo human glioblastomas

Benjamin M. Ellingson, Timothy F. Cloughesy, Whitney B. Pope, Taryar M. Zaw, Heidi Phillips, Shadi Lalezari, Phioanh L. Nghiemphu, Hassana Ibrahim, Kourosh M. Naeini, Robert J. Harris, Albert Lai

Journal:

Year:

2012

Language:

english

File:

PDF, 2.11 MB

english, 2012

19

Glioblastoma therapy in the elderly: one age does not fit all

Phioanh Leia Nghiemphu, Timothy Cloughesy

Journal:

The Lancet Oncology

Year:

2012

Language:

english

File:

PDF, 99 KB

english, 2012

20

Relationship between Tumor Enhancement, Edema, IDH1 Mutational Status, MGMT Promoter Methylation, and Survival in Glioblastoma

Carrillo, J. A., Lai, A., Nghiemphu, P. L., Kim, H. J., Phillips, H. S., Kharbanda, S., Moftakhar, P., Lalaezari, S., Yong, W., Ellingson, B. M., Cloughesy, T. F., Pope, W. B.

Journal:

American Journal of Neuroradiology

Year:

2012

Language:

english

File:

PDF, 1011 KB

english, 2012

21

Evaluation of High Ipsilateral Subventricular Zone Radiation Therapy Dose in Glioblastoma: A Pooled Analysis

Lee, Percy, Eppinga, Wietse, Lagerwaard, Frank, Cloughesy, Timothy, Slotman, Benjamin, Nghiemphu, Phioanh L., Wang, Pin-Chieh, Kupelian, Patrick, Agazaryan, Nzhde, Demarco, John, Selch, Michael T., St

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

2013

Language:

english

File:

PDF, 715 KB

english, 2013

22

Imaging biomarkers for antiangiogenic therapy in malignant gliomas

Leu, Kevin, Pope, Whitney B, Cloughesy, Timothy F, Lai, Albert, Nghiemphu, Phioanh L, Chen, Wei, Liau, Linda M, Ellingson, Benjamin M

Journal:

Year:

2013

Language:

english

File:

PDF, 6.18 MB

english, 2013

23

C-terminally truncated form of αB-crystallin is associated with IDH1 R132H mutation in anaplastic astrocytoma

Avliyakulov, Nuraly K., Rajavel, Kavitha S., Le, Khanh Minh T., Guo, Lea, Mirsadraei, Leili, Yong, William H., Liau, Linda M., Li, Sichen, Lai, Albert, Nghiemphu, Phioanh L., Cloughesy, Timothy F., Li

Journal:

Journal of Neuro-Oncology

Year:

2014

Language:

english

File:

PDF, 1.14 MB

english, 2014

24

Altered functional connectivity of the default mode network in diffuse gliomas measured with pseudo-resting state fMRI

Harris, Robert J., Bookheimer, Susan Y., Cloughesy, Timothy F., Kim, Hyun J., Pope, Whitney B., Lai, Albert, Nghiemphu, Phioanh L., Liau, Linda M., Ellingson, Benjamin M.

Journal:

Journal of Neuro-Oncology

Year:

2014

Language:

english

File:

PDF, 297 KB

english, 2014

25

Differential Gene Expression in Glioblastoma Defined by ADC Histogram Analysis: Relationship to Extracellular Matrix Molecules and Survival

Pope, W. B., Mirsadraei, L., Lai, A., Eskin, A., Qiao, J., Kim, H. J., Ellingson, B., Nghiemphu, P. L., Kharbanda, S., Soriano, R. H., Nelson, S. F., Yong, W., Phillips, H. S., Cloughesy, T. F.

Journal:

American Journal of Neuroradiology

Year:

2012

Language:

english

File:

PDF, 1.43 MB

english, 2012

26

High Order Diffusion Tensor Imaging in Human Glioblastoma

Cloughesy, Timothy F., Lai, Albert, Nghiemphu, Phioanh L., Liau, Linda M., Pope, Whitney B., Ellingson, Benjamin M.

Journal:

Academic Radiology

Year:

2011

Language:

english

File:

PDF, 1.38 MB

english, 2011

27

PET Parametric Response Mapping for Clinical Monitoring and Treatment Response Evaluation in Brain Tumors

Ellingson, Benjamin M., Chen, Wei, Harris, Robert J., Pope, Whitney B., Lai, Albert, Nghiemphu, Phioanh L., Czernin, Johannes, Phelps, Michael E., Cloughesy, Timothy F.

Journal:

Year:

2013

Language:

english

File:

PDF, 2.16 MB

english, 2013

28

Short-interval estimation of proliferation rate using serial diffusion MRI predicts progression-free survival in newly diagnosed glioblastoma treated with radiochemotherapy

Zaw, Taryar M., Pope, Whitney B., Cloughesy, Timothy F., Lai, Albert, Nghiemphu, Phioanh L., Ellingson, Benjamin M.

Journal:

Journal of Neuro-Oncology

Year:

2014

Language:

english

File:

PDF, 442 KB

english, 2014

29

Nonlinear distortion correction of diffusion MR images improves quantitative DTI measurements in glioblastoma

Woodworth, Davis C., Pope, Whitney B., Liau, Linda M., Kim, Hyun J., Lai, Albert, Nghiemphu, Phioanh L., Cloughesy, Timothy F., Ellingson, Benjamin M.

Journal:

Journal of Neuro-Oncology

Year:

2014

Language:

english

File:

PDF, 1.12 MB

english, 2014

30

Pretreatment ADC Histogram Analysis Is a Predictive Imaging Biomarker for Bevacizumab Treatment but Not Chemotherapy in Recurrent Glioblastoma

Ellingson, B. M., Sahebjam, S., Kim, H. J., Pope, W. B., Harris, R. J., Woodworth, D. C., Lai, A., Nghiemphu, P. L., Mason, W. P., Cloughesy, T. F.

Journal:

American Journal of Neuroradiology

Year:

2014

Language:

english

File:

PDF, 1.37 MB

english, 2014

31

Tumor-Suppressive miR148a Is Silenced by CpG Island Hypermethylation in IDH1-Mutant Gliomas

Li, S., Chowdhury, R., Liu, F., Chou, A. P., Li, T., Mody, R. R., Lou, J. J., Chen, W., Reiss, J., Soto, H., Prins, R., Liau, L. M., Mischel, P. S., Nghiemphu, P. L., Yong, W. H., Cloughesy, T. F., La

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 1.41 MB

english, 2014

32

Recurrent Glioblastoma Treated with Bevacizumab: Contrast-enhanced T1-weighted Subtraction Maps Improve Tumor Delineation and Aid Prediction of Survival in a Multicenter Clinical Trial

Ellingson, Benjamin M., Kim, Hyun J., Woodworth, Davis C., Pope, Whitney B., Cloughesy, Jonathan N., Harris, Robert J., Lai, Albert, Nghiemphu, Phioanh L., Cloughesy, Timothy F.

Journal:

Year:

2014

Language:

english

File:

PDF, 2.29 MB

english, 2014

33

Assessing the significance of chromosomal aberrations in cancer: Methodology and application to glioma

Beroukhim, R., Getz, G., Nghiemphu, L., Barretina, J., Hsueh, T., Linhart, D., Vivanco, I., Lee, J. C., Huang, J. H., Alexander, S., Du, J., Kau, T., Thomas, R. K., Shah, K., Soto, H., Perner, S., Pre

Journal:

Proceedings of the National Academy of Sciences

Year:

2007

Language:

english

File:

PDF, 780 KB

english, 2007

34

The L84F polymorphic variant of human O6-methylguanine-DNA methyltransferase alters stability in U87MG glioma cells but not temozolomide sensitivity

Remington, M., Chtchetinin, J., Ancheta, K., Nghiemphu, P. L., Cloughesy, T., Lai, A.

Journal:

Year:

2008

Language:

english

File:

PDF, 1.71 MB

english, 2008

35

Increased sensitivity to radiochemotherapy in IDH1 mutant glioblastoma as demonstrated by serial quantitative MR volumetry

Tran, A. N., Lai, A., Li, S., Pope, W. B., Teixeira, S., Harris, R. J., Woodworth, D. C., Nghiemphu, P. L., Cloughesy, T. F., Ellingson, B. M.

Journal:

Year:

2014

Language:

english

File:

PDF, 440 KB

english, 2014

36

Phase II Study of Bevacizumab Plus Temozolomide During and After Radiation Therapy for Patients With Newly Diagnosed Glioblastoma Multiforme

Lai, A., Tran, A., Nghiemphu, P. L., Pope, W. B., Solis, O. E., Selch, M., Filka, E., Yong, W. H., Mischel, P. S., Liau, L. M., Phuphanich, S., Black, K., Peak, S., Green, R. M., Spier, C. E., Kolevsk

Journal:

Journal of Clinical Oncology

Year:

2011

Language:

english

File:

PDF, 201 KB

english, 2011

37

Hypervascular tumor volume estimated by comparison to a large-scale cerebral blood volume radiographic atlas predicts survival in recurrent glioblastoma treated with bevacizumab

Leu, Kevin, Enzmann, Dieter R, Woodworth, Davis C, Harris, Robert J, Tran, Anh N, Lai, Albert, Nghiemphu, Phioanh L, Pope, Whitney B, Cloughesy, Timothy F, Ellingson, Benjamin M

Journal:

Year:

2014

Language:

english

File:

PDF, 2.72 MB

english, 2014

38

Relationship between Survival and Edema in Malignant Gliomas: Role of Vascular Endothelial Growth Factor and Neuronal Pentraxin 2

Carlson, M. R.J., Pope, W. B., Horvath, S., Braunstein, J. G., Nghiemphu, P., Tso, C.-L., Mellinghoff, I., Lai, A., Liau, L. M., Mischel, P. S., Dong, J., Nelson, S. F., Cloughesy, T. F.

Journal:

Clinical Cancer Research

Year:

2007

Language:

english

File:

PDF, 353 KB

english, 2007

39

Identifying the mesenchymal molecular subtype of glioblastoma using quantitative volumetric analysis of anatomic magnetic resonance images

Naeini, K. M., Pope, W. B., Cloughesy, T. F., Harris, R. J., Lai, A., Eskin, A., Chowdhury, R., Phillips, H. S., Nghiemphu, P. L., Behbahanian, Y., Ellingson, B. M.

Journal:

Year:

2013

Language:

english

File:

PDF, 439 KB

english, 2013

40

Probabilistic Radiographic Atlas of Glioblastoma Phenotypes

Ellingson, B. M., Lai, A., Harris, R. J., Selfridge, J. M., Yong, W. H., Das, K., Pope, W. B., Nghiemphu, P. L., Vinters, H. V., Liau, L. M., Mischel, P. S., Cloughesy, T. F.

Journal:

American Journal of Neuroradiology

Year:

2013

Language:

english

File:

PDF, 3.38 MB

english, 2013

41

Persistent Diffusion-Restricted Lesions in Bevacizumab-Treated Malignant Gliomas Are Associated with Improved Survival Compared with Matched Controls

Mong, S., Ellingson, B. M., Nghiemphu, P. L., Kim, H. J., Mirsadraei, L., Lai, A., Yong, W., Zaw, T. M., Cloughesy, T. F., Pope, W. B.

Journal:

American Journal of Neuroradiology

Year:

2012

Language:

english

File:

PDF, 2.78 MB

english, 2012

42

Impact of 3,4-Dihydroxy-6-18F-Fluoro-L-Phenylalanine PET/CT on Managing Patients with Brain Tumors: The Referring Physician's Perspective

Walter, F., Cloughesy, T., Walter, M. A., Lai, A., Nghiemphu, P., Wagle, N., Fueger, B., Satyamurthy, N., Phelps, M. E., Czernin, J.

Journal:

Journal of Nuclear Medicine

Year:

2012

Language:

english

File:

PDF, 672 KB

english, 2012

43

Quantitative volumetric analysis of conventional MRI response in recurrent glioblastoma treated with bevacizumab

Ellingson, B. M., Cloughesy, T. F., Lai, A., Nghiemphu, P. L., Mischel, P. S., Pope, W. B.

Journal:

Year:

2011

Language:

english

File:

PDF, 419 KB

english, 2011

44

PTEN dosage is essential for neurofibroma development and malignant transformation

Gregorian, C., Nakashima, J., Dry, S. M., Nghiemphu, P. L., Smith, K. B., Ao, Y., Dang, J., Lawson, G., Mellinghoff, I. K., Mischel, P. S., Phelps, M., Parada, L. F., Liu, X., Sofroniew, M. V., Eilber

Journal:

Proceedings of the National Academy of Sciences

Year:

2009

Language:

english

File:

PDF, 1.60 MB

english, 2009

45

MRI perfusion measurements calculated using advanced deconvolution techniques predict survival in recurrent glioblastoma treated with bevacizumab

Harris, Robert J., Cloughesy, Timothy F., Hardy, Anthony J., Liau, Linda M., Pope, Whitney B., Nghiemphu, Phioanh L., Lai, Albert, Ellingson, Benjamin M.

Journal:

Journal of Neuro-Oncology

Year:

2015

Language:

english

File:

PDF, 1.22 MB

english, 2015

46

Relationship Between [18F]FDOPA PET Uptake, Apparent Diffusion Coefficient (ADC), and Proliferation Rate in Recurrent Malignant Gliomas

Karavaeva, Elena, Harris, Robert J., Leu, Kevin, Shabihkhani, Maryam, Yong, William H., Pope, Whitney B., Lai, Albert, Nghiemphu, Phioanh L., Liau, Linda M., Chen, Wei, Czernin, Johannes, Cloughesy, T

Journal:

Molecular Imaging and Biology

Year:

2015

Language:

english

File:

PDF, 4.40 MB

english, 2015

47

Correlation of 6-18F-Fluoro-L-Dopa PET Uptake with Proliferation and Tumor Grade in Newly Diagnosed and Recurrent Gliomas

Fueger, B. J., Czernin, J., Cloughesy, T., Silverman, D. H., Geist, C. L., Walter, M. A., Schiepers, C., Nghiemphu, P., Lai, A., Phelps, M. E., Chen, W.

Journal:

Journal of Nuclear Medicine

Year:

2010

Language:

english

File:

PDF, 1.16 MB

english, 2010

48

Safety of anticoagulation use and bevacizumab in patients with glioma

Nghiemphu, P., Green, R. M., Pope, W. B., Lai, A., Cloughesy, T. F.

Journal:

Year:

2008

Language:

english

File:

PDF, 2.00 MB

english, 2008

49

Quantification of nonenhancing tumor burden in gliomas using effective T2 maps derived from dual-echo turbo spin-echo MRI

Ellingson, B. M., Lai, A., Nguyen, H. N., Nghiemphu, P. L., Pope, W. B., Cloughesy, T. F.

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 3.82 MB

english, 2015

50

Graded functional diffusion map-defined characteristics of apparent diffusion coefficients predict overall survival in recurrent glioblastoma treated with bevacizumab

Ellingson, B. M., Cloughesy, T. F., Lai, A., Mischel, P. S., Nghiemphu, P. L., Lalezari, S., Schmainda, K. M., Pope, W. B.

Journal:

Year:

2011

Language:

english

File:

PDF, 475 KB

english, 2011

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